mavorixafor will boost the stage or outcome of codeine by influencing hepatic enzyme CYP2D6 metabolism. Contraindicated. Mavorixafor (a robust CYP2D6 inhibitor) is contraindicated with medicines which can be highly dependent on CYP2D6 for clearance.Ache that is delicate to moderate is often treated with Makatussi. There are further uses for Makatus